USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P63098 USC-OGP 2-DE database:  P63098 P63098 General information about the entry View entry in simple text format Entry name CANB1_HUMAN Primary accession number P63098 Secondary accession number(s) P06705 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Calcineurin subunit B type 1; AltName: Full=Protein phosphatase 2B regulatory subunit 1; AltName: Full=Protein phosphatase 3 regulatory subunit B alpha isoform 1;. Gene name Name=PPP3R1 Synonyms=CNA2, CNB Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0253: pI=4.58; Mw=16298 Cross-references UniProtKB/Swiss-Prot P63098; CANB1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CANB1_HUMAN Primary accession number P63098 Secondary accession number(s) B2RC10 B5MDU4 P06705 P15117 Q08044 Q53SL0 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 145) Name and origin of the protein Description RecName: Full=Calcineurin subunit B type 1; AltName: Full=Protein phosphatase 2B regulatory subunit 1; AltName: Full=Protein phosphatase 3 regulatory subunit B alpha isoform 1; Gene name Name=PPP3R1 Synonyms=CNA2, CNB Encoded on Name=PPP3R1; Synonyms=CNA2, CNB Keywords 3D-structure; Calcium; Cell membrane; Complete proteome; Cytoplasm; Direct protein sequencing; Lipoprotein; Membrane; Metal-binding; Myristate; Phosphoprotein; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M30773; AAB08721.1; -; mRNA EMBL CR456938; CAG33219.1; -; mRNA EMBL AK314893; BAG37407.1; -; mRNA EMBL AC017083; AAY14715.1; -; Genomic_DNA EMBL CH471053; EAW99878.1; -; Genomic_DNA EMBL BC027913; AAH27913.1; -; mRNA CCDS CCDS46310.1; -; . PIR A33391; A33391; . RefSeq NP_000936.1; NM_000945.3; . UniGene Hs.280604; -; . PDB 1AUI; X-ray; 2.10 A; B=2-170 PDB 1M63; X-ray; 2.80 A; B/F=2-170 PDB 1MF8; X-ray; 3.10 A; B=1-170 PDB 2P6B; X-ray; 2.30 A; B/D=16-170 PDB 3LL8; X-ray; 2.00 A; B/D=16-170 PDB 4F0Z; X-ray; 1.70 A; B=1-170 PDB 4OR9; X-ray; 2.23 A; B=1-170 PDB 4ORA; X-ray; 2.75 A; B=1-170 PDB 4ORC; X-ray; 2.70 A; B=1-170 PDB 5SVE; X-ray; 2.60 A; B=1-170 PDBsum 1AUI; -; . PDBsum 1M63; -; . PDBsum 1MF8; -; . PDBsum 2P6B; -; . PDBsum 3LL8; -; . PDBsum 4F0Z; -; . PDBsum 4OR9; -; . PDBsum 4ORA; -; . PDBsum 4ORC; -; . PDBsum 5SVE; -; . DisProt DP00565; -; . ProteinModelPortal P63098; -; . SMR P63098; -; . BioGrid 111526; 35; . DIP DIP-6096N; -; . IntAct P63098; 6; . MINT MINT-1339650; -; . STRING 9606.ENSP00000234310; -; . DrugBank DB04906; ISA247; . DrugBank DB08231; MYRISTIC ACID; . iPTMnet P63098; -; . PhosphoSitePlus P63098; -; . SwissPalm P63098; -; . BioMuta PPP3R1; -; . DMDM 52000904; -; . OGP P63098; -; . EPD P63098; -; . MaxQB P63098; -; . PaxDb P63098; -; . PeptideAtlas P63098; -; . PRIDE P63098; -; . TopDownProteomics P63098; -; . Ensembl ENST00000234310; ENSP00000234310; ENSG00000221823; . GeneID 5534; -; . KEGG hsa:5534; -; . UCSC uc002sei.2; human; . CTD 5534; -; . DisGeNET 5534; -; . GeneCards PPP3R1; -; . HGNC HGNC:9317; PPP3R1; . HPA CAB005610; -; . HPA HPA047157; -; . MIM 601302; gene; . neXtProt NX_P63098; -; . OpenTargets ENSG00000221823; -; . PharmGKB PA33681; -; . eggNOG KOG0034; Eukaryota; . eggNOG COG5126; LUCA; . GeneTree ENSGT00860000133729; -; . HOVERGEN HBG105307; -; . InParanoid P63098; -; . KO K06268; -; . PhylomeDB P63098; -; . TreeFam TF105558; -; . Reactome R-HSA-111447; Activation of BAD and translocation to mitochondria; . Reactome R-HSA-180024; DARPP-32 events; . Reactome R-HSA-2871809; FCERI mediated Ca+2 mobilization; . Reactome R-HSA-4086398; Ca2+ pathway; . Reactome R-HSA-5607763; CLEC7A (Dectin-1) induces NFAT activation; . ChiTaRS PPP3R1; human; . EvolutionaryTrace P63098; -; . GeneWiki PPP3R1; -; . GenomeRNAi 5534; -; . PRO PR:P63098; -; . Proteomes UP000005640; Chromosome 2; . Bgee ENSG00000221823; -; . CleanEx HS_PPP3R1; -; . ExpressionAtlas P63098; baseline and differential; . Genevisible P63098; HS; . GO GO:0005955; C:calcineurin complex; NAS:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005739; C:mitochondrion; IEA:GOC; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell; . GO GO:0005509; F:calcium ion binding; NAS:UniProtKB; . GO GO:0004723; F:calcium-dependent protein serine/threonine phosphatase activity; NAS:UniProtKB; . GO GO:0005516; F:calmodulin binding; NAS:UniProtKB; . GO GO:0019904; F:protein domain specific binding; IPI:BHF-UCL; . GO GO:0001569; P:branching involved in blood vessel morphogenesis; IEA:Ensembl; . GO GO:0033173; P:calcineurin-NFAT signaling cascade; IDA:BHF-UCL; . GO GO:0001837; P:epithelial to mesenchymal transition; IEA:Ensembl; . GO GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome; . GO GO:0007507; P:heart development; IEA:Ensembl; . GO GO:0060487; P:lung epithelial cell differentiation; IEA:Ensembl; . GO GO:0022011; P:myelination in peripheral nervous system; IEA:Ensembl; . GO GO:0051531; P:NFAT protein import into nucleus; IEA:Ensembl; . GO GO:0051533; P:positive regulation of NFAT protein import into nucleus; IDA:BHF-UCL; . GO GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome; . GO GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL; . GO GO:0007223; P:Wnt signaling pathway; calcium modulating pathway; TAS:Reactome CDD cd00051; EFh; 2; . Gene3D 1.10.238.10; -; 1; . InterPro IPR011992; EF-hand-dom_pair; . InterPro IPR018247; EF_Hand_1_Ca_BS; . InterPro IPR002048; EF_hand_dom; . Pfam PF13499; EF-hand_7; 2; . SMART SM00054; EFh; 4; . SUPFAM SSF47473; SSF47473; 1; . PROSITE PS00018; EF_HAND_1; 4; . PROSITE PS50222; EF_HAND_2; 4; .

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